Cruises to Panama

Compare prices for 184 matching cruises

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Panama Canal Round-trip Miami: Mexico, Belize & Costa Rica Cruise
Norwegian Jewel
10 Night Cruise Onboard Norwegian Jewel
Cruise operated by Norwegian Cruise Line
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Panama Canal - Ocean to Ocean Holiday Cruise
Island Princess
16 Night Cruise Onboard Island Princess
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Cruise operated by Princess Cruises
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Southern Caribbean Cruise
Serenade of the Seas
7 Night Cruise Onboard Serenade of the Seas
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Cruise operated by Royal Caribbean
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Southern Caribbean & Panama Canal: Abc Islands Cruise
Rotterdam
21 Night Cruise Onboard Rotterdam
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Cruise operated by Holland America Line
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Panama Canal with Costa Rica & Caribbean Cruise
Caribbean Princess
12 Night Cruise Onboard Caribbean Princess
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Cruise operated by Princess Cruises
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Panama, strategically located at the crossroads of the Americas, offers a unique and historically significant cruising experience.

A cruise provides a comfortable and convenient way to witness the canal's impressive locks, explore lush rainforests, and discover Panama's rich history and vibrant cities. It's a chance to see a vital waterway that connects the world and experience the natural beauty and cultural heritage of Panama.

Popular Cruise Ports in Panama

Colón, Panama
Colón
Located on the Caribbean side of the Panama Canal, Colón offers access to the canal's Gatun Locks, nearby rainforests, and historical sites, providing a glimpse into Panama's history and natural beauty.
Fuerte Amador, Panama
Fuerte Amador
This causeway connects several small islands in the Pacific, offering stunning views of (and access to) Panama City, the Bridge of the Americas, recreational areas and restaurants.
Panama Canal (Transit), Panama
Panama Canal (Transit)
A Panama Canal transit cruise offers a unique opportunity to witness firsthand a remarkable feat of engineering while traversing between the Atlantic and Pacific Oceans, often combined with visits to diverse ports in the Caribbean and Central/South America.
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